Alli (Orlistat 60mg)

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Alli (Orlistat 60mg)
Alli (Orlistat 60mg) 1
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Alli can help you lose weight by reducing the amount of fat you absorb during digestion.

What is Alli?

Alli is a clinically proven weight loss aid used to treat adults who are overweight and have a BMI of 28 or higher. Alli is designed to help you to lose more weight than by dieting alone as long as you follow a reduced calorie, low fat diet and exercise regularly.

It contains the active ingredient orlistat which is the only medicine licensed in the EU for weight loss.

Alli is not an appetite suppressant, stimulant, fat blocker, or a pill with magical properties. You still have to eat a healthy low calorie, lower fat diet and exercise regularly, but Alli helps you lose weight faster.

How does Alli work?

Unlike other over the counter slimming pills, Alli works in a unique way to target the fat in the digestive system. Its active ingredient, orlistat, attaches to the enzyme lipase that breaks down the fat from a meal, effectively preventing it from digesting fat.

It stops about a quarter of fat from your diet from being absorbed and this fat will pass out of your body in your stools.

As a result, the fat cannot go through the gut lining and be stored. The fat just passes through the body and is excreted so calories do not turn into extra weight.

How effective is Alli?

For every 2kg you lose through dieting and exercise, Alli diet pills can help you lose an additional 1kg. It has been clinically proven to help you lose 50% more weight than dieting alone.

In a clinical study, visceral fat was reduced in over 70% of Alli users who followed a reduced calorie, lower-fat diet.

How do I take Alli?

The Alli tablets should be swallowed whole with water three times day during meal times. It can be taken one hour before, during or an hour after the meal to be effective. Don’t take it if you are having a meal without any fat or if you skip a meal. Also, you should not take the medication more than three times a day.

Since Alli affects how the body absorbs different foods, your body may struggle to extract adequate amounts of certain nutrients from your regular diet alone. You should supplement your diet with a multivitamin specifically designed to replenish the vital vitamins and minerals lost. We recommended the OneVit Complete multivitamin, a daily supplement that rebalances a wide range of important micronutrients, such as vitamins A,D, E and K.

Can I take Alli?

Alli is only licensed to adults with a BMI of 28 and over and should be taken in conjunction with a healthy low calorie diet. Alli does not require a fat-free diet, just reduced fat. In fact, fat is an important part of a healthy diet in moderate amounts. It helps the body absorb vitamins and other essential functions in the body.

Body Mass Index (BMI) and Alli

Alli may be suitable if you have a body mass index (BMI) of over 28. You can quickly calculate your BMI by entering your height and weight into our BMI calculator.

How fast does Alli work?

Alli is the only clinically proven weight loss medication in the UK. Alli starts to work as soon as you take it to decrease the amount of fat absorbed into your body and you can see the results depending on your diet and exercise.

Side Effects

The most common side effects of Alli (Orlistat 60mg) include:

  • oily rectal discharge
  • passing gas with oily discharge
  • urgent need to have a bowel movement
  • oily or fatty stools
  • increased number of bowel movements
  • being unable to control your bowel movements

All medications can cause side effects. You may not experience any of them. The majority of the common side effects experienced with Alli are related to the way it works in your digestive system. These side effects are usually mild, occur at the beginning of treatment, and particularly after high fat meals. Normally these symptoms will subside as you continue treatment and follow your recommended diet.

The most common side effects of Alli, which may affect more than 1 in 10 people include headache, abdominal pain or discomfort, urgent or increased need to open the bowels, wind, oily discharge or oily/fatty stools.

Written and reviewed by our qualified team

GPhC Number: 2088658

Ana Carolina Goncalves
Authored by: Ana Carolina Goncalves Superintendent
Pharmacist

GPhC Number: 2225869

Rehma Gill
Reviewed by: Rehma Gill Pharmacy
Manager

Find out more about our team of medical content authors and how we ensure the accuracy of our content with our content guidelines.

Content last updated: 04 Jun 2025

Alli Reviews

Overall Rating
9.6 / 10
Ratings Distribution
5 stars
351
4 stars
68
3 stars
9
2 stars
1
1 star
2

Based on 431 independent customer reviews taken by Feefo, Google and Trustpilot.

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Feefo logo
"Very reliable"

Product Review:

Taking Alli has definitely worked for me. I have been dieting and exercising but felt I needed a bit of help keeping to a sensible fat intake level. This product helped me to achieve that. I have lost between 2-3lbs on a weekly basis. Very happy and would recommend this product to anyone

Service Review:

Very happy with this company. Easy to find what I needed, straightforward to order and extremely quick to deliver. Very efficient from start to finish

Review from: Trustpilot

TickVerified Buyer

Product Review:

Love this product. Works so well and can’t wait for my next one xx

Review from: Trustpilot

TickVerified Buyer

"Great professional service"

Product Review:

Lost 4lb in the first week of taking these. And weight slowly coming of

Service Review:

The service is thorough and quick delivery. It is up to the customer to answer the questions truthfully and seek doctors advice on certain medication you may wish to order from the web site. I would not hesitate to order from pyramids again

Review from: Feefo

TickVerified Buyer

"Excellent service "

Product Review:

Excellent service, great product

Service Review:

Fast delivery, competitive prices

Review from: Feefo

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Product Review:

Amazing! Such a great product

Service Review:

Brilliant

Review from: Feefo

TickVerified Buyer

"Fast flawless service and delivery"

Product Review:

Seems to be working. Suits my lifestyle.

Service Review:

You order online...you want a seamless fast drama free delivery. This was my experience with Pharmica.

Review from: Feefo

TickVerified Buyer

Product Review:

Im very happy with the diet pills they have really helping me to loose weight. good for the money and i will be happy to use you again thank you.

Review from: Trustpilot

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Product Review:

I'm seeing great progress progress in my weight loss

Service Review:

Thank you we had a fast deliver and good quality product.

Review from: Feefo

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"Excellent "

Product Review:

Brilliant results easy to use

Service Review:

Very good and professional service

Review from: Feefo

TickVerified Buyer

Product Review:

This has help me and is my saviour, along with a low calorie, and low fat and salt diet I have lost weight, and, I will continue with this helping aid for as long as I am able to. This product has made it so much easier to lose weight, it has given me confidence to continue with it. Also, unlike before, a diet of any kind has made me miserable, not with this product, I am happy, my portion size have become smaller not because I have to, but because My stomach has become smaller and I really cannot eat any more.

Review from: Trustpilot

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Your privacy is important to us. That’s why we’ve taken every step to ensure your order arrives in the most discreet way possible.

From start to finish, your purchase is handled with complete confidentiality. You’ll never see our brand name on your bank statement, bills or delivery papers.

All our parcels are sent in plain, unmarked packaging with no logos, no product descriptions and no indication of what’s inside.

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